Liverpool welcome Reading to Anfield still searching for their first home win of the season.
Liverpool were held to a goalless draw at home to Stoke last time out, while Reading picked up a 2-2 draw at Swansea before the international break.
The Royals won their last visit to Anfield in an FA Cup replay in January 2010 which was Brian McDermott's first victory as manager of Reading.
Much of the focus will be on Reds striker Luis Suarez after he came in for criticism for going to ground too easily against Stoke.
Suarez will lead the line for Liverpool who are short of attacking options after Fabio Borini was ruled out for three months.
The Royals are unbeaten in their last three games and they will be hoping to move out of the bottom three with a positive result at Anfield.
Liverpool goalkeeper Jose Reina faces a late fitness test on a minor hamstring problem sustained on international duty with Spain prior to the game against Reading.
Striker Fabio Borini has been ruled out for up to three months with a fractured foot but defenders Jose Enrique and Jon Flanagan returned to training this week.
Midfielder Jonjo Shelvey is available again after serving a three-match suspension.
Reading forward Noel Hunt is a doubt for the game on Merseyside because of a heel problem.
Midfielder Mikele Leigertwood has been passed fit after recovering from a dead leg.
Reading boss Brian McDermott has no further injury concerns as the club seek their first Premier League win of the season.