Liverpool welcomes Southampton to Anfield aiming to cement their place at the top of the Premier League.
Liverpool saw their 100% start to the season ended after being held to a 2-2 draw at Swansea on Monday and they will be keen to return to winning ways against Southampton.
The home side will again look to the in-form Daniel Sturridge for goals after becoming the first player in Liverpool's Premier League history to score in the team's opening four games of the season.
Southampton have endured an inconsistent start to the campaign, winning one game, drawing two and losing the other in their opening four games.
Mauricio Pochettino's men have struggled for goals having scored two goals so far in the Premier League and they have yet to score in open play.
Liverpool defender Daniel Agger is expected to return to face Southampton after missing Monday's draw at Swansea with a side strain.
Playmaker Philippe Coutinho is out for several weeks after undergoing a shoulder operation so the likes of Iago Aspas and Raheem Sterling will be pushing for a recall.
The match marks the completion of striker Luis Suarez's 10-game ban, which was carried over from last season.
Southampton left-back Luke Shaw is fit for the Premier League trip to Anfield.
The teenager limped off in last weekend's 0-0 draw with West Ham, but Mauricio Pochettino has revealed he has overcome that knock.
Fellow left-back Danny Fox remains a doubt with an ankle complaint and Tadanari Lee may also miss out.