Surprise package Hull City travel to Anfield on Saturday aiming to shock league leaders Liverpool.
The game is the first league meeting in 48 years between the two clubs as Liverpool play host to sixth-placed City.
The Tigers have already beaten Arsenal at Emirates Stadium and they ran Manchester United close at Old Trafford, and they will be aiming to put a dent in Liverpool's title aspirations.
The Reds have drawn their last two league games at Anfield and they will be determined to pick up all three points to cement their position at the top of the table.
The hosts are still without star striker Fernando Torres as he continues his recovery from a hamstring strain.
Robbie Keane will be hoping to get the nod to start after impressing in the midweek UEFA Champions League win over PSV Eindhoven following his omission from the starting line-up in last weekend's victory at Blackburn.
Steven Gerrard, Xabi Alonso, Dirk Kuyt and Pepe Reina are all expected to be recalled after being rested for the Champions League tie.
Fabio Aurelio misses out again with a calf problem meaning Andrea Dossena will battle it out with Emiliano Insua for the left-back slot.
Tigers boss Phil Brown has promised to travel to Anfield with a positive approach and he is set to resist the temptation to employ a defensive formation.
Marlon King is expected to lead the attack despite his off-field difficulties this week.
City will be without striker Caleb Folan who is still suffering with a knee injury.
Full-back Andy Dawson is ruled out with an Achilles problem meaning Sam Ricketts will continue at left-back.
Nick Barmby will be hoping to get the chance to face his former club, while Dean Windass will again be restricted to a role on the bench.
Long-term absentees Anthony Gardner and Craig Fagan are still a way off a return but both are expected to resume full-time training next week.
Possible starting XIs
Liverpool: Reina, Arbeloa, Carragher, Agger, Dossena, Kuyt, Alonso, Mascherano, Reira, Gerrard, Keane.
Hull: Myhill, McShane, Turner, Zayatte, Ricketts, Marney, Boateng, Ashbee, Barmby, Geovanni, King.
The game is the first league meeting in 48 years between the two clubs as Liverpool play host to sixth-placed City.
The Tigers have already beaten Arsenal at Emirates Stadium and they ran Manchester United close at Old Trafford, and they will be aiming to put a dent in Liverpool's title aspirations.
The Reds have drawn their last two league games at Anfield and they will be determined to pick up all three points to cement their position at the top of the table.
The hosts are still without star striker Fernando Torres as he continues his recovery from a hamstring strain.
Robbie Keane will be hoping to get the nod to start after impressing in the midweek UEFA Champions League win over PSV Eindhoven following his omission from the starting line-up in last weekend's victory at Blackburn.
Steven Gerrard, Xabi Alonso, Dirk Kuyt and Pepe Reina are all expected to be recalled after being rested for the Champions League tie.
Fabio Aurelio misses out again with a calf problem meaning Andrea Dossena will battle it out with Emiliano Insua for the left-back slot.
Tigers boss Phil Brown has promised to travel to Anfield with a positive approach and he is set to resist the temptation to employ a defensive formation.
Marlon King is expected to lead the attack despite his off-field difficulties this week.
City will be without striker Caleb Folan who is still suffering with a knee injury.
Full-back Andy Dawson is ruled out with an Achilles problem meaning Sam Ricketts will continue at left-back.
Nick Barmby will be hoping to get the chance to face his former club, while Dean Windass will again be restricted to a role on the bench.
Long-term absentees Anthony Gardner and Craig Fagan are still a way off a return but both are expected to resume full-time training next week.
Possible starting XIs
Liverpool: Reina, Arbeloa, Carragher, Agger, Dossena, Kuyt, Alonso, Mascherano, Reira, Gerrard, Keane.
Hull: Myhill, McShane, Turner, Zayatte, Ricketts, Marney, Boateng, Ashbee, Barmby, Geovanni, King.